Fu, D., Calvo, J.A., Samson, L.D., 2012. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat Rev Cancer 12, 104–120. doi:10.1038/nrc3185 Sources… Leggi tutto »DNA Damage Repairing Single-strand damage (SSD)
DSD REPAIR (BRCA1-2 depending) Fu, D., Calvo, J.A., Samson, L.D., 2012. Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat Rev… Leggi tutto »DNA double-strand break (DSB) repair
Lauren Pecorino “Molecular Biology of Cancer -Mechanisms, Targets, and Therapeutics. Oxford University 2012 Synthetic lethality. Normal cells have functional DNA repair pathways so that they… Leggi tutto »SYNTHETIC LETHAL STRATEGY
Filmati 1-3 1- Dna Replication; 2- DNA fork coupling; 3- Mitosis and cell division 1- 2- 3-
Filmati 4-6 4 – Transcription; 5- Transcription regulation 6- mRNA Splicing 4- 5- 6-
7-The regulation of splicesome-mediated splicing 8- Translation 9- REgulation of Translation 7- 8- 9-
Filmati 10-12 10 – Generation and action of siRNAs and miRNAs 11- Ubiquitin 12- Non-homologous end joining 4- 5- 6-
Filmati 13-16 13 – Homology-dependent double strand break repair 14- Holliday junction resolution 15- DNA cut and paste transposition 16- the retroviral and retroviral-like transposon… Leggi tutto »Part: 13-16/ 16 video:- Craig et al: Molecular Biology 2e Oxford Academic (Oxford University Press) Ultimo aggiornamento in data 02 dic 2014